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DAILY MCQ 60 ANSWER

basiliximab  is a IL 1 AgonistIL-2 receptor antagonistIL-6 antagonistIL-11 agonist ANSWER:  IL-2 receptor antagonist REF: KDT 7E/ P 884 Basiliximab: anti CD-25 antibody with higher affinity for the IL-2 receptorIt has  shorter plasma t½ of 1 week Clinical use of basiliximab with combination regimens used to prevent renal and other transplant rejection reactioncombination regimens for maintenance of graft. For more MCQs and concepts  become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/

DAILY MCQ 60

basiliximab  is a IL 1 AgonistIL-2 receptor antagonistIL-6 antagonistIL-11 agonistFor more MCQs and concepts  become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/

DAILY MCQ 59 answer

Drug of choice for resistant rheumatic chorea refractory to treatment  is A.        haloperidol B.        IV immunoglobulin C.        sodium Valproate D.        carbamazepine Ref: Harrison 19 E/P 2153 Treatment of rheumatic chorea: mild cases: be managed by providing a calm environment carbamazepine or sodium Valproate is preferred to haloperidol response seen after 2 weeks and continued for 2 weeks after symptoms fall down  severe chorea: Severe or refractory cases: corticosteroids(Prednisone or Prednisolone)  are effective and lead to more rapid symptom reduction in chorea to be selected  in  severe or refractory cases Severe chorea refractory to other treatments  IV immunoglobulin : For more MCQs and concepts  become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/

DAILY MCQ 59

Drug of choice for resistant rheumatic chorea refractory to treatment  is A.        haloperidol B.        IV immunoglobulin C.        sodium Valproate D.        carbamazepine  For more MCQs and concepts  become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/

DAILY MCQ 58 answer

atypical antipsychotic drug  with maximum  hyperprolactinemia is olanzapine clozapine ziprasidone resperidone ref: GG 12e/ p 423 atypical  antipsychotics agents have decreased affinity for D2 receptors so, hyperprolactinemia adverse effect is reduced in patients but  risperidone and paliperidone are exceptions because both agents cause dose-dependent increases in prolactin resperidone: Fewer side effects than Clozapine Blocks selective D2, NA  & 5-HT2 Becomes "typical" at high doses leading to EPS (>6mg) Long acting injectable formulation Shares sedation, tachycardia, orthostatic hypotension and elevated prolactin No agranulocytosis risks Hyperprolactinemia note: among atypical antipsychotics risperidone, paliperidone have high D2 affinity  and blocks it causing Hyperprolactinemia

PILLS 20

beta 2 agonist having anabolic action is clenbuterol

DAILY MCQ 58

atypical antipsychotic drug  with maximum  hyperprolactinemia is olanzapineclozapineziprasidoneresperidoneFor more MCQs and concepts  become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/