Which of the following is false about Pramlinitide?
Used in Type 1 and Type 2 DM
Acts through Amylin receptor
increases insulin release
causes weight loss
answer: increases insulin release
ref: GG 13E/P 886
Pramlintide:
acts through the amylin receptor
reduces glucagon secretion
delays gastric emptying
feeling of satiety is seen
doesn’t increase insulin release
Adverse Effects:
nausea and hypoglycemia(MC)( when used with insulin)
Therapeutic Uses.:
approved for treatment of types 1 and 2 diabetes as an adjunct in patients who take insulin with meals
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