Which of the following describes Mechanism of action of centrally acting muscle relaxant?
Decreases voluntary power and does not paralyse
Increases voluntary power and does not paralyse
Decrease muscle tone without reducing voluntary power
Decreases voluntary power and Cause muscle paralysis
Ref: KD Tripathi - Essentials of Medical Pharmacology 7th Edition: 357
Centrally acting muscle relaxants
reduce skeletal muscle tone
voluntary power of muscle is intact
depress Polysynaptic pathways in the ascending reticular formation leading to mild sedation
no effect is seen on neuromuscular transmission or muscle fibres
note:
Peripherally acting muscle relaxant act at neuromuscular junction, causes muscle paralysis and decreases voluntary power
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