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DAILY MCQ 11 ANSWER

which of the following is a Diuretic Conivaptan Rolophylline Both A and B None answer: 3 GG 13E/P 542 Conivaptan Vassopressin antagonist DIURETIC used In SIADH RolophyllinE adenosine A1 receptor blocker DIURETIC tried for CHF For more MCQs and concepts  become pro member by clicking belowhttps://drpharmacologist.testpress.in/products/pro-members/

Reasoning

Can we use Same  lignocaine used  for local anaesthesia for ventricular arrhythmia IV..if yes/ no  why?

DAILY MCQ 9 answer

A hypothyroid Patient was taking levothyroxine from last 1 year. Now the patient is being diagnosed with Celiac disease. What should you do with levothyroxine dose?A. IncreaseB. DecreaseC.keep it Same D. Can't say anything ANSWER IS A.  Increase Because in Celiac disease levothyroxine absorption decreases its dose needs to be increased 

why allopurinol increases acute attack of gouty arthritis

 allopurinol increases acute attack of gouty arthritis  during the early months of allopurinol therapy because it increases  mobilization of tissue stores of uric acid so thereby causing  hyperuricaemia leading to increased precipitaion of uric acid in joint and acute attack clinical implication so initial period when giving allopurinol,  always give it along with NSAIDs or COLCHICINE to prevent this attack

concept 1

Glucagon  is a specific antidote for beta blocker  toxicity: in  beta-blocker poisoning  beta receptors are blocked in heart leading to decrease in HR, FOC and conduction so GPCR of Beta 1 receptor in heart is blocked, so what to do now?give a drug which acts through different type of GPCR So,  Glucagon acts through its own GPCR and independent of the β adrenergic receptor and has chronotropic and inotropic effects on the heart  in beta-blocker poisoning  glucagon is a physiological antidote note: why not atropine an antidote as it also increases HR and conduction it is not much effective compared to Glucagon, and doesnot increase FOC it is used if there is bradycardia