Published on Aug 19, 2018
daily MCQ 37 answer

Which of the following describes Mechanism of action of centrally acting muscle relaxant?

  1. Decreases voluntary power and does not paralyse
  2. Increases voluntary power and does not paralyse
  3. Decrease muscle tone without reducing voluntary power
  4. Decreases voluntary power  and Cause muscle paralysis

Ref:  KD Tripathi - Essentials of Medical Pharmacology 7th Edition: 357

Centrally acting muscle relaxants

  • reduce skeletal muscle tone
  • voluntary power of muscle is intact
  • depress Polysynaptic pathways in the ascending reticular formation leading to   mild sedation
  • no effect is seen  on neuromuscular transmission  or muscle fibres 

note:

Peripherally acting muscle relaxant act at neuromuscular junction, causes muscle paralysis and decreases voluntary power

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