Intravenous formulation used  for closure of persistent patent ductus arteriosus in premature infants is

1. Indomethacin
2. ibuprofen
3. Ketoprofen
4. both A and B

ANSWER both A and B

GG 13E/P 697

drugs for closure of persistent patent ductus arteriosus in premature infants

• IV  Indomethacin is approved
• IV  formulation of ibuprofen is an alternative for the treatment of patent ductus Arteriosus
• so both  Indomethacin and ibuprofen are used as Intravenous formulation