Published on Jul 11, 2019
Target 200MCQ 39 answer

Amiloride is DOC for Lithium induced Diabetes insipidus because
A. Amiloride inhibits ADH action
B. Amiloride inhibits lithium entry through epithelial Na channel
C. Hyperkalemia induced by amiloride decreases water output
D. Amiloride increases ADH action


Answer b

Lithium inhibits action of ADH and causes Diabetes insipidus. Amiloride inhibits entry of lithium through epithelial Na channels and antagonizes lithium action on ADH. so amiloride is DOC for Lithium induced Diabetes insipidus



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