Treatment to eradicate salmonella carrier state is by Ciprofloxacin, 500 mg orally twice a day for 2 weeks Ciprofloxacin, 750 mg orally twice a day for 4 weeks Ciprofloxacin, 500 mg orally twice a day for 8 weeks Ciprofloxacin, 250 mg orally twice a day for 4 weeks For more MCQs and concepts become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/
Which of the following CCB decreases aldosterone secretion A. Nifedipine B. Amlodipine C. Cilnidipine D. Efondipine correct answer is D Efondipine Efondipine newer CCBhas T type and L type CCB blocking propertyapproved for angina and hypertensionblocking T type calcium channel in adrenal gland decreases aldosterone secretion
which of the following alpha glucosidase inhibitor doesn't require dose reduction in renal failure A. Acrabose B. Voglibose C. Miglitolol D. None of the above ref: Masanori Ab et al., Antidiabetic Agents in Patients with Chronic Kidney Disease and End-Stage Renal Disease on Dialysis: Metabolism and Clinical Practice. Current Drug Metabolism, 2011, 12, 57-69. Alpha glucosidase inhibitors Acarbose Dose adjustment required in renal failure Miglitol Dose adjustment required in renal failure Voglibose No dose adjustment necessary in renal failure
Which of the following drugs decrease Thyroid binding globulinA. EstrogensB. TamoxifenC. glucocorticoidsD. MethadoneANSWER C. glucocorticoidsREF: GG 12E / page 1135 Estrogens,Tamoxifen, Methadone increase Thyroid binding globulin and increase thyroxine binding to Thyroid binding globulin Factors that Alter Binding of Thyroxine to Thyroxine-Binding Globulin
Which of the following CCB decreases aldosterone secretion A. Nifedipine B. Amlodipine C. Cilnidipine D. Efondipine
Tafenoquine is recently approved for treatment of Plasmodium ovale malaria Plasmodium vivax malaria Plasmodium falciparum malaria Plasmodium knowlesi malaria ANSWER:Plasmodium vivax malaria ref: GG 13E/P 980 https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210795s000lbl.pdf Tafenoquine oral tablet an antimalarial indicated for the radical cure of Plasmodium vivax malaria in patients aged 16 years and older who are receiving appropriate antimalarial therapy for acute P. vivax infection not used to treat acute infection active against pre-erythrocytic (liver) and erythrocytic (asexual) forms as well as gametocytes of P. vivax G6PD Deficiciency: causes hemolyisis not be given to pregnant and lactating mother For more MCQs and concepts become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/
Heparin causes hyperkalemia by inhibiting epithelial Na Channels by releasing potassium from mast cells by inhibiting the synthesis of aldosterone by releasing potassium from osteoclasts answer: by inhibiting the synthesis of aldosterone ref: GG 13E/P 592 Heparin can inhibit the synthesis of aldosterone by the adrenal glands and occasionally causes hyperkalemia For more MCQs and concepts become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/
Ciraparantag Binds to dabigatranrivaroxabanLMWHAll of the aboveanswer: All of the abovegg 13E/P 595 Ciraparantag is a synthetic, small cationic molecule it is reported to bind dabigatran, rivaroxaban, apixaban, and edoxaban, as well as heparin and LMWH
5 hours if drug typically follows first order kinetics 400 mg500 mg600 mg700 mg answer is 600 mg..watch video for explanation For more MCQs and concepts become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/
Which of the following glucocorticoid has most salt retaining property? prednisolonebetamethasonedexamethasonehydrocortisoneanswer is hydrocortisone