Bevacizumab is used as single agent in following cancer

1. lung cancer
2. renal cell cancer
3. Breast cancer
4. colorectal cancer

answer is B

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CMDT 2018 page 1638

Bevacizumab

• a humanized antibody directed against VEGF-A
• was the first FDAapproved molecule that specifically targeted angiogenesis.
• As a single agent, it delays progression of renal-cell cancer
• in combination with cytotoxic chemotherapy, effectively treats lung, colorectal, and breast cancers

Single agent chemotherapy for renal cell cancer

• Sunitinib or temsirolimus or bevacizumab or sorafenib or pazopanib or axitinib  or interleukin