Immediate-release formulation of venlafaxine can induce

1. sustained systolic  hypertension
2. sustained diastolic hypertension
3. sustained diastolic hypotension
4. sustained systolic hypotension

GG 13E/P 273

immediate-release formulation of Venlafaxine

• can induce sustained diastolic hypertension (diastolic blood pressure > 90 mm Hg at consecutive weekly visits) in 10%–15% of patients at higher doses
• This effect of venlafaxine may not be associated simply with inhibition of NET because duloxetine does not share this side effect 

THE risk is reduced with the extended-release form

note:

• This effect of venlafaxine may not be associated simply with inhibition of NET because duloxetine does not share this side effect 

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