Drug of choice for resistant rheumatic chorea refractory to treatment  is

A.        haloperidol

B.        IV immunoglobulin

C.        sodium Valproate

D.        carbamazepine

Ref: Harrison 19 E/P 2153

Treatment of rheumatic chorea:

mild cases:

• be managed by providing a calm environment
• carbamazepine or sodium Valproate is preferred to haloperidol
• response seen after 2 weeks and continued for 2 weeks after symptoms fall down

 severe chorea:

Severe or refractory cases:

• corticosteroids(Prednisone or Prednisolone)  are effective and lead to more rapid symptom reduction in chorea
• to be selected  in  severe or refractory cases

Severe chorea refractory to other treatments

 IV immunoglobulin :

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