Choose the incorrect statement regarding drug absorption

1. First pass metabolism reduces bioavailability
2. highly ionized molecule are absorbed from stomach
3. heparin not absorbed due to its large size
4. most common method of drug absorption is by passive diffusion

ANS: B highly ionized molecule are absorbed from stomach

ref: KDT 7E/P 15

High yield concepts about absorption

• First pass metabolism is inversely proportional to bioavailability , so reduces bioavailability
• highly ionized molecule are not at all absorbed from stomach or intestine or from any place
•  heparin not absorbed due to its large size and it is highly ionized
• most common method of drug absorption is by passive diffusion

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