congratulations
on this occasionI would like to congratulate Dr. Shrey Bhatt, for his achievement of AIR 40 in this NEET PG he was a promember of this app.i wish him all the good luck in the future
on this occasionI would like to congratulate Dr. Shrey Bhatt, for his achievement of AIR 40 in this NEET PG he was a promember of this app.i wish him all the good luck in the future
Which of the following property of the drug will enable it to be used in low concentration? (AIIMS Nov. 2005) High affinity High specificity Low specificity High stability For more MCQs and concepts become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/
elevation of glucose by corticosteroids is counteracted by insulin is an example CHEMICAL antagonism competitive antagonism non competitive antagonism physiological antagonism answer physiological antagonism REF: KAT 14E/P 25 physiological antagonism: it is an antagonism between endogenous regulatory pathways mediated by different receptors glucocorticoids and insulin act on quite distinct receptor effector systems and regulate glucose histamine and adrenaline act at different recptor and cause bronchoconstriction and bronchodilatation respectively For more MCQs and concepts become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/
Which of the following statement is correct regarding the given DRCs? AIIMS nov 16 A and B are full agonists C is non competitive antagonist B more potent than A A is more efficacious than B For more MCQs and concepts become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/
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which of the following acts through membrane bound guanylyl cyclase Insulin herceptin Nitric oxidenesiritide answer is 4 nesiritide membrane bound guanylyl cyclase Tyrosine phosphatases Natriuretic peptides acts through this they increase c GMP EXAMPLE: Nesiritide note: NO acts through soluble guanylcyclase For more MCQs and concepts become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/
Which of the following acts through tyrosine kinase type receptor?(AIIMS pattern) a. Salbutomol b. Cetrizine c. Spironolactone d. Insulin like growth factor REF: KDT 8E/P 59 answer D Insulin like growth factor REF: KDT 7E/P 101 Salbutomol acts on Beta receptor which is a GPCRCetrizine acts on H2 receptor which is a GPCRSpironolactone acts on Aldosterone receptor which is a nuclear receptor Insulin like growth factor acts through tyrosine kinase type receptor For more MCQs and concepts become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/
A drug Y takes 6 hours to reach its 50% steady state plasma concentration when given IV. what is the elimination half-life of the drug Y? A. 4 h B. 6 h C. 12 h D. 24 h answer is B 6hrs The THUMB rules for time to steady-state plasma concentration it takes 4–5 t ½ to reach clinical steady-state plasma concentration at one half life it reaches 50% of steady-state plasma concentration from the question 6hrs required for 50% steady-state plasma concentration which is equal to its half life, so half life of drug is 6hrs Steady concentration plasma concentration is achieved when a constant amount of drug is added every half life 1st t1/2 50% 2nd t1/2 (50+25) 75% 3rd t1/2 (50+25+12.5) 87.5% 4th t1/2 (50+25+12.5+6.25) 93.75% 5th t1/2 (50+25+12.5+6.25+ 3.125) 96.97% so from above concept at one half life it reaches 50% of steady-state plasma concentration from the question 6hrs required for 50% steady-state plasma concentration which is equal to its half life, so half life of drug is 6hrs For more MCQs and concepts become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/
Which of the following drugs is not metabolized by acetylation? Dapsone PAS Clonazepam lorazepam answer: 4. lorazepam ref; KDT P: 24 Drugs undergoing acetylation: cool SHIP cool- clonazepam S- Sulfonamide, Dapsone, PAS, H-Hydralazine I- Isoniazid P-Procainamide For more MCQs and concepts become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/
Calculate hepatic clearance of a drug with hepatic blood flow of 1500 ml/min and hepatic extraction ratio of 0.5 1000ml per min 1500ml per min 1125ml per min 750ml per min answer: 750ml/min Hepatic clearance = hepatic blood flow X hepatic extraction ratio = 1500 x 0.5 = 750ml/min For more MCQs and concepts become pro member by clicking below https://drpharmacologist.testpress.in/products/pro-members/